Citazione:

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Sodium orthovanadate is the chemical compound Na3VO4 and contains the tetrahedral VO43#8722;.[1] It is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue. The VO43- ion binds reversibly to the active sites of most protein tyrosine phosphatases.

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Citazione:

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In biochemistry, fluoride salts are commonly used to inhibit the activity of phosphatases, such as serine/threonine phosphatases.[7] It may do this by replacing the nucleophilic hydroxyl ion in these enzymes' active sites.

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